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Review Article
Neonatology (Perinatology)
Short- and long-term outcomes of very low birth weight infants in Korea: Korean Neonatal Network update in 2019
Jang Hoon Lee, YoungAh Youn, Yun Sil Chang; Korean Neonatal Network
Clin Exp Pediatr. 2020;63(8):284-290.   Published online February 5, 2020
The Korean Neonatal Network (KNN) has collected population-based data for very low birth weight infants (VLBWIs) born in Korea since 2013. The survival rate of all VLBWIs was 86% in Korea. The overall prevalence of cerebral palsy was 6.2%–6.6%. Bilateral blindness and hearing loss were reported in 0.2%–0.3%, 0.8%–1.9%, respectively. The KNN has published annual reports and papers for facilitating the improvement of VLBWIs outcome in Korea.
Original Article
Developmental and Behavioral Medicine
Validity of the Korean Developmental Screening Test for very-low-birth-weight infants
Chae Young Kim, Euiseok Jung, Byong Sop Lee, Ki-Soo Kim, Ellen Ai-Rhan Kim
Clin Exp Pediatr. 2019;62(5):187-192.   Published online March 20, 2019

Purpose: The importance of the neurodevelopmental outcomes of very-low-birth-weight (VLBW) infants has been emphasized as their mortality rate has markedly improved. This study aimed to assess the validity of the Korean Developmental Screening Test (K-DST), a developmental screening tool approved by the Korean Society of Pediatrics, for the timely diagnosis of neurodevelopmental delay in VLBW infants. Methods: Subjects included VLBW infants...
Neonatology (Perinatology)
Association between vitamin D level at birth and respiratory morbidities in very-low-birth-weight infants
Ian Kim, Sung Shin Kim, Jee In Song, Seock Hwa Yoon, Ga Young Park, Yong-Wha Lee
Clin Exp Pediatr. 2019;62(5):166-172.   Published online October 24, 2018

Purpose: This study aimed to evaluate vitamin D status at birth in very-low-birth-weight infants (VLBWIs: <1,500 g) and to determine the association between vitamin D level and respiratory morbidity. Methods: A retrospective study was conducted at Soonchunhyang University Bucheon Hospital between November 2013 and November 2017. We collected blood samples and data on respiratory morbidity from 230 VLBWIs on the first...
Postdischarge growth assessment in very low birth weight infants
Joon-Sik Park, Jungho Han, Jeong Eun Shin, Soon Min Lee, Ho Seon Eun, Min-Soo Park, Kook-In Park, Ran Namgung
Clin Exp Pediatr. 2017;60(3):64-69.   Published online March 27, 2017
Purpose

The goal of nutritional support for very-low-birth-weight (VLBW) infants from birth to term is to match the in utero growth rates; however, this is rarely achieved.

Methods

We evaluated postdischarge growth patterns and growth failure in 81 Korean VLBW infants through a retrospective study. Weight and height were measured and calculated based on age percentile distribution every 3 months until age 24...

A study on the measurement of the nucleated red blood cell (nRBC) count based on birth weight and its correlation with perinatal prognosis in infants with very low birth weights
Tae Hwan Kil, Ji Yeon Han, Jun Bum Kim, Gyeong Ok Ko, Young Hyeok Lee, Kil Young Kim, Jae Woo Lim
Clin Exp Pediatr. 2011;54(2):69-78.   Published online February 28, 2011
Purpose

The aim of this study was conducted to investigate the mean nRBC count in very low births weight infants (VLBWIs) and to determine the usefulness of the nRBC as an independent prognostic factors of perinatal complications in VLBWIs.

Methods

This study was conducted on 112 VLBWIs who were hospitalized in the neonatal intensive care unit (NICU) of the author's hospital within the...

Changes in the outcomes of neonatal intensive care unit at a single center over 12 years
Hyun-Hee Lee, Tae-Yeon Kim, Seon-Hee Shin, Tae-Jung Sung
Clin Exp Pediatr. 2009;52(8):881-887.   Published online August 15, 2009

Purpose:The survival rate of very low birth weight infant (VLBWI) had increased as a result of advances in neonatal intensive care. We evaluated the changes in outcomes of VLBWI who admitted to the neonatal care unit of Hallym University Kangnam Sacred Heart Hospital. Methods:Retrospective review of 339 VLBWI who were born from 1st January 1997 to 31th December 2008 were performed. Outcomes including survival...
Growth and clinical efficacy of fortified human milk and premature formula on very low birth weight infants
Heewon Chueh, Myo Jing Kim, Young-A Lee, Jin-A Jung
Clin Exp Pediatr. 2008;51(7):704-712.   Published online July 15, 2008
Purpose : A prospective, controlled trial was conducted to evaluate growth, efficacy, safety and nutritional status for very low birth weight infants fed with human milk fortified with Maeil human milk fortifier (Maeil HMF ; Maeil Dairies Co., Ltd.). Methods : We enrolled 45 premature infants with a birth weight <1,500 g and gestational age <33 weeks, who were born at...
The effect of restricted fluid intakes in the first week of life on the risk of bronchopulmonary dysplasia and patent ductus arteriosus in very low birth weight infants
Hoe Kyoung Koo, Eun Na Choi, Ran Namgung, Min Soo Park, Kook In Park, Chul Lee
Clin Exp Pediatr. 2007;50(6):536-542.   Published online June 15, 2007
Purpose : We investigated the effects of restricted fluid in the first 7 days of life on the risk of bronchopulmonary dysplasia (BPD) or patent ductus arteriosus (PDA) in very low birth weight (VLBW) infants. Methods : Eighty three VLBW infants who lived more than 28 days were selected. The amount of daily maintenance fluid was determined by calculation of insensible...
Catch-up growth and development of very low birth weight infants
Tae Ho Ma, Kyung Ah Kim, Sun Young Ko, Yeon Kyung Lee, Son Moon Shin
Clin Exp Pediatr. 2006;49(1):29-33.   Published online January 15, 2006
Purpose : The aim of this study was to analyze the results and contributing factors of catch-up growth in very low birth weight infants(VLBWI) at the corrected age of 2 years. In addition, we looked for a relationship between the catch-up growth and the development by the bayley scales of infant development II(BSID II). Methods : A retrospective analysis by...
Survival Rate in Very Low Birth Weight Infants
Jae Ju Cho, Soon Bum Lee, Woo Sung Park, Young Pyo Chang
Clin Exp Pediatr. 2004;47(5):505-509.   Published online May 15, 2004
Purpose : We observed changes in the outcome of very low birth weight infants(VLBWI) admitted to the neonatal intensive care unit(NICU) of Dankook University Hospital(DKUH) in the last six years. Methods : The distribution of birth weight and gestational age, survival rate, neonatal complications, and causes of death for 228 VLBWI who had been admitted to DKUH from 1st January...
Changes in Incidence, Survival Rate and Morbidity of Very Low Birth Weight Infants
Young Ok Kim, Sun Hui Kim, Chang Yee Cho, Young Youn Choi, Jin Hwa Kook, Tae Ju Hwang
Clin Exp Pediatr. 2003;46(8):769-776.   Published online August 15, 2003
Purpose : The survival rate of very low birth weight infants(VLBWI) has improved by virtue of specialized neonatal care. This study was performed to analyze the changes in incidence, survival rate and morbidity of VLBWI who admitted to Chonnam National University Hospital from 1996 to 2001. Methods : We enrolled 565 VLBWI, and compared the incidence and the survival rate according...
Changes in the Outcomes of Very Low Birth Weight Infants
Shung Shin Kim, Moon Hee Kim, Jae Won Shin, Sun Young Ko, Eun Kyung Lee, Yun Sil Chang, I Seok Kang, Won Soon Park, Mun Hyang Lee, Sang Il Lee, Heung Jae Lee
Clin Exp Pediatr. 2002;45(7):828-835.   Published online July 15, 2002
Purpose : The outcomes of infants weighing less than 1,500 gm(very low birth weight infant : VLBWI) reflect recent progress in neonatal intensive care. In this study, we analyzed changes over time in survival rate and morbidity of VLBWIs during the past seven years. Methods : A retrospective review of medical records was analyzed for VLBWIs admitted to the neonatal intensive...
Growth and Neurodevelopmental Outcome at 15 Months of Corrected Age in Very Low Birth Weight Infants with Chronic Lung Disease
Seon Young Kim, Chang Yee Cho, Young Youn Choi
Clin Exp Pediatr. 2001;44(10):1112-1118.   Published online October 15, 2001
Purpose : This study was performed to compare the growth and neurodevelopmental outcome at 15 months of corrected age in very-low-birth weight infants between chronic lung disease(CLD) group and the control group. Methods : Very-low-birth-weight infants who were admitted and survived in the NICU(neonatal intensive care units) of Chonnam Univeristy Hospital from Jan. 1997 to Jan. 2000 were divided into...
Case Report
An Infant with Vertical Transmission of Human Immunodeficiency Virus Infection Detected Due to Failure to Thrive
Byung Wook Eun, Ho Kyung Lim, Yun Kyung Kim, Yuong Ho Kwak, Jung Youn Hong, He Sun Jung, Kyung Mo Kim, Hoan Jong Lee
Clin Exp Pediatr. 2001;44(5):592-596.   Published online May 15, 2001
Five to fifteen percent of patients affected by human immunodeficiency virus(HIV) are children in developing countries. In Korea, most of HIV infections in children have been transfusion-related, and cases of vertical transmission have been very rare so far and are usually suspected due to a maternal positive history. We experienced a case of vertical transmission of HIV in a 19...
Original Article
Growth and Neurodevelopmental Outcome on Very Low Birth Weight Infants During 2 Years
Eun Suk Kim, Jong Uk Kim, Oh Kyung Lee, Wan Soeb Kim
Clin Exp Pediatr. 1996;39(5):641-651.   Published online May 15, 1996
Purpose : By rapid development of neonatal intensive care from 1960, we are able to expect the long survival of the very low birth weight infants. But, there were high risk of poor growth, neurodevelopmental delay, deafness, and blindness in very low birth weight infants. So, it is important to follow-up after discharge. We try to compare normal term infants with...
Effect of Intravenous Immunoglobulin(IVIG) on Renal Function in Very Low Birth Weight Infants
Hwa Young Jang, Haeng Mi Kim
Clin Exp Pediatr. 1996;39(4):475-481.   Published online April 15, 1996
Purpose : This study was conducted to evaluate the effect of IVIG infusion on renal function in VLBW infants. IVIG has been proved quite safe in neonates given prophylactic and therapeutic doses. But nephrotoxicity is not recognized as adverse in IVIG therapy, only several previous adult cases have been noted. Methods : For a total of ten VLBW infants who had...
Clinical Study on Very Low Birth Weight Infants
Sha Young Choi, Dae Young Jang, Oh Kyung Lee, Wan Seob Kim
Clin Exp Pediatr. 1994;37(5):628-635.   Published online May 15, 1994
Medical records of very low birth weight infants weighing less than 1500 grams at birth were reviewed and analyzed. One hundred and forty three infants who were admitted to neonatal intensive care unit of Presbyterian Medical Center, including those who were born and transferred from other hospitals, from January 1987 to December 1991 were examined and the following results were obtained; 1)...
Clinical Observation on Very Low Birth Weight Infants
Jong Soo Lee, Mi Young Yeo, Byung Hak Lim, Sang Geel Lee
Clin Exp Pediatr. 1992;35(1):44-50.   Published online January 15, 1992
Charts of very low birth weight infants weighing less than 1500 gms at birth were revieved and the results were analyzed. Infants were 152 in numbers, admitted to nursery in Fatima Hospital from January 1986 to December 1989 including outborns. Results were as follow: 1) The incidence of very low birth weight was 5.78/1000 among 26270 newborn infants. 2) Maternal high...
Clinical and statistical observation for very low birth weight infants.
Sung Shin Park, Ji Hee Jung, Dong Hwan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1991;34(12):1629-1640.   Published online December 31, 1991
We made clinical and statistical observation of 90 very low birth weight infants who were admitted at Soonchunhyang university hospital during the 6 years period from January 1985 through December 1990. The result obtained were as follows: 1) The incidence of very low birth weight infant during 6 years period was 0.68%, and the mortality rate was 488/1000 very low birth weight infants. 2) There was no obvious...
Clinical Survey of Very low Birth Weight Infant.
Seong Sook Jeon, Wha Mo Lee, Yang Sook Choi, Son Sang Seo
Clin Exp Pediatr. 1988;31(9):1120-1125.   Published online September 30, 1988
A clinical survey of Very Low Brith Weight Infant was done on 27,170 infants bom at II Sin Christian Hospital between Jan. 1 1983 and Dec. 31 1986. The results were as follows; 1) The incidence of VLBWI in the 27,170 births was 1.0%, and there was no annual variation. 2) Among 10,749 multiparaty there was a higher incidence of VLBWI (1.4%) compared to that in primiparity...
The Result of Intensive Care on the very Low Birth Weight Infants(1001~1500gm).
Seo Jeong Kim, Ran Namgung, Chul Lee, Dong Gwan Han
Clin Exp Pediatr. 1988;31(1):29-39.   Published online January 31, 1988
The clinical study on the results of intensive care was performed on the 137 very low birth weight infants with birth weight of 1001-1500 gram who were admitted to the neonatal intensive care unit of Severance hospital from 1981 to 1986. The results were as follows. 1) The range of gestational age of very low birth weight infants was from 22 to 40 weeks, most predominantly...
Clinical Observation on Very Low Birth Weight Infants.
Ran Ah Kim, Yeong Jee Kim, Kyung Hee KIm, Keun Lee
Clin Exp Pediatr. 1986;29(1):26-31.   Published online January 31, 1986
Charts of very low birth weight infants weighing less than 1,500 grams at birth were reviewed and the results analyzed. Infants were 107 in numbers, admitted to NICU, Ewha Womans University Hospital for the period of 4 years from July 1980 to June 1984 including outborns. Results were as follows: 1) Incidence of very low birth weight infant was 1....
Follow Up Study of the Low Birth Weight Infants Less than Birth Weight 1,500 grams.
Hyun Sook Yoon
Clin Exp Pediatr. 1984;27(7):648-657.   Published online July 31, 1984
The growth and development of very low birth weight infants was evaluated in 92 of 114 survivors out of 384 babies weighing less than 1,500 grams who were born from January 1976 to December 1979 in Il-Sin Hospital. The mean birth weight and gestional age were 1,378±15.2 grams and 31±0.6 wks. Apgar score 5 or more at five minutes were...
Case Report
A Case of Vertically Transmitted Neonatal Hepatitis B with Pancytopenia.
Young Chang Kim, Jae Oak Park
Clin Exp Pediatr. 1982;25(7):737-742.   Published online July 31, 1982
A newborn infant, who was low-birth weight(1,780gm), showed severe degree of jaundice on second day of life and skin color became dark greenish-yellow and moderate hepatosplenomegaly was noted on physical examination. Results of liver function test & radioimmuniassay for hepatitis B antigen of both infant and mother suggested that neonatal hepatitis B seemed to occure transplacentally during pregnancy from infected...
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